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David Devilbiss, Ph.D.

Assistant Professor

Science Center 


Drexel University 
Department of Neurobiology and Anatomy, Ph.D., 2002



Research Interests

Our current research is focused on understanding the neuromodulation-related changes in neural coding that underlies flexible cognitive and behavioral functions. We use a variety of techniques including single neuron and multichannel electrophysiology, computational neuroscience, neuropharmacology, neurochemistry, anatomy, and behavioral techniques to interrogate the regulation of information processing across large networks of neurons in awake and behaving rats with normal cognitive function, attention deficit-hyperactivity disorder (ADHD), stress. In addition, the lab is building on emerging evidence linking the LC-NE system in the cognitive sequelae of concussion and mild-traumatic brain injury as well as back-translating recent work in industry on concussion diagnostics.


(Updated July 2019)

  1. Devilbiss DM, Etnoyer-Slaski JL, Dunn E, Dussourd CR, Kothare MV, Martino SJ, Simon AJ. Effects of Exercise on EEG Activity and Standard Tools Used to Assess Concussion. J Healthc Eng, 2019: April 2019.
  2. Devilbiss DM. Consequences of tuning network function by tonic and phasic locus coeruleus output and stress: Regulating detection and discrimination of peripheral stimuli. Brain Res, 1709: 16-27, April 2019.
  3. Hupalo S, Martin AJ, Green RK, Devilbiss DM, Berridge CW. Prefrontal Corticotropin-Releasing Factor (CRF) Neurons Act Locally to Modulate Frontostriatal Cognition and Circuit Function. J Neurosci, 39(11): 2080-90, March 2019.
  4. Devilbiss DM, Spencer RC, Berridge CW. Stress Degrades Prefrontal Cortex Neuronal Coding of Goal-Directed BehaviorCereb Cortex, 27(5): 2970-83, May 2017.
  5. Spencer RC, Devilbiss DM, Berridge CW. The cognition-enhancing effects of psychostimulants involve direct action in the prefrontal cortex. Biol Psychiatry, 77(11): 940-50, June 2015.
  6. Ghorbanian P, Devilbiss DM, Hess T, Bernstein A, Simon AJ, Ashrafiuon H. Exploration of EEG features of Alzheimer's disease using continuous wavelet transform. Med Biol Eng Comput, 53(9): 843-55, September 2015.
  7. Ghorbanian P, Devilbiss DM, Verma A, Bernstein A, Hess T, Simon AJ, Ashrafiuon H. Identification of resting and active state EEG features of Alzheimer's disease using discrete wavelet transform.
    Ann Biomed Eng, 41(6): 1243-57, June 2013.
  8. Devilbiss DM, Jenison RL, Berridge CW. Stress-induced impairment of a working memory task: role of spiking rate and spiking history predicted dischargePLoS Comput Biol, 8(9):e1002681, September 2012.
  9. Devilbiss DM, Waterhouse BD, Berridge CW, Valentino R. Corticotropin-releasing factor acting at the locus coeruleus disrupts thalamic and cortical sensory-evoked responsesNeuropsychopharmacology, 37(9): 2020-30, August 2012.
  10. Berridge CW, Shumsky JS, Andrzejewski ME, McGaughy JA, Spencer RC, Devilbiss DM, Waterhouse BD. Differential sensitivity to psychostimulants across prefrontal cognitive tasks: differential involvement of noradrenergic α1- and α2 -receptorsBiol Psychiatry, 71(5): 467-73, March 2012.
  11. Devilbiss DM, Waterhouse BD. Phasic and tonic patterns of locus coeruleus output differentially modulate sensory network function in the awake ratJ Neurophysiol, 105(1): 69-87, January 2011.
  12. Leiser SC, Dunlop J, Bowlby MR, Devilbiss DMAligning strategies for using EEG as a surrogate biomarker: a review of preclinical and clinical researchBiochem Pharmacol, 81(12): 1408-21, June 2011.